Develop a 4 page analysis of the Saama Technologies case study located in the module.  As part of your analysis, be sure to address the following (Note:  There is no need to concern yourself with any discussion questions that may be in the case):

*  Clearly and effectively discuss and apply the concepts from this weeks chapter (and previous weeks as appropriate) of the text to the case.  Note: Case analyses that are overly general and do not comprehensively address the strategic management concepts from the text will receive low grades.

*  Apply at least three of the following strategic analysis text tools.  Be sure that the focus of your analysis is on the following strategic analysis tools.  In addition, please make these some of your papers section titles:

“Weapons” to compete with rivals
Strategic group mapping (bubble map)
Competitor analysis
Ratio analysis
Financial analysis
VRIN tests
Generic strategy analysis
Industry attractiveness test
Cost of entry test
Better off test

*  Perform real analysis on the case (tables/charts/financial analysis)

*  Charts and tables need to be professionally assembled with effective titles and labels

*  Avoid retelling the case and assume the professor has read it

*  Provide a set of clear and specific recommendations to move the organization forward.

*  Double spaced, 12 pt font, times roman, APA style, section titles use lower case bold, title page, no headers or footers

* Avoid cut-and-paste of charts, pictures and tables from another source (your own creative work is needed).

* Is well organized with section titles

* Strategic management terms need to be used to support your thoughtful ideas.

*  Avoid a conversational/first person tone in an analysis

Saama Technologies: Growth Through a Focused
Vertical Market Strategy

Case

Author: Mohanbir Sawhney & Pallavi Goodman
Online Pub Date: January 02, 2019 | Original Pub. Date: 2018
Subject: New Product Design & Marketing, Creativity & Innovation in Business, Strategic Management &
Planning
Level: Intermediate | Type: Direct case | Length: 6000 words
Copyright:

© 2018 Kellogg School of Management, Northwestern University

Organization: Saama Technologies | Organization size: Large
Region: Northern America | State:
Industry: Manufacture of basic pharmaceutical products and pharmaceutical preparations
Originally Published in:
Sawhney, M., & Goodman, P. (2018). Saama Technologies: Growth through a focused vertical market
strategy. 5–218–251. Evanston, IL: Kellogg School of Management, Northwestern University.
Publisher: Kellogg School of Management
DOI: http://dx.doi.org/10.4135/9781526491930 | Online ISBN: 9781526491930

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http://dx.doi.org/10.4135/9781526491930

© 2018 Kellogg School of Management, Northwestern University

This case was prepared for inclusion in SAGE Business Cases primarily as a basis for classroom discussion
or self-study, and is not meant to illustrate either effective or ineffective management styles. Nothing herein
shall be deemed to be an endorsement of any kind. This case is for scholarly, educational, or personal use
only within your university, and cannot be forwarded outside the university or used for other commercial
purposes. 2019 SAGE Publications Ltd. All Rights Reserved.

This content may only be distributed for use within Franklin Pierce University.

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http://dx.doi.org/10.4135/9781526491930

Abstract

After a successful transition from a projects-based IT business services company to a platform-
driven analytics company, Saama’s core leadership team gathered in 2017 to brainstorm the
next phase of its growth. The year before, the team had decided to narrow its target market to
the life sciences vertical. Saama now had to decide how to execute on this focused strategy
by choosing a growth pathway within the life sciences vertical. Saama’s leadership team was
considering three alternatives: acquiring new customer accounts, developing existing customer
accounts, or developing new products by harnessing artificial intelligence (AI) and blockchain
technologies. The team had to evaluate these growth pathways in terms of both short-and long-
term revenue potential, as well as their potential for sustaining Saama’s competitive advantage.

Case
In October 2017, the leaders of Saama Technologies gathered for a meeting at their Silicon Valley headquar-
ters in Campbell, California, to review three years of financial performance. Since its founding twenty years
ago, Saama had evolved from a project-based IT services company into a platform-driven analytics compa-
ny. In 2016, Saama’s leadership team had decided to narrow its market focus to one vertical market: the life
sciences industry. Based on this focused vertical market strategy, Saama had launched a new cloud-based
platform called the Life Science Analytics Cloud (LSAC).

The decision to focus on the life sciences vertical had been successful, and Saama had picked up several
Fortune 500 customers from the industry. By narrowing its focus, however, Saama had also reduced its total
addressable market (TAM) to less than a third of its earlier TAM, which had included other vertical markets
such as insurance, consumer packaged goods (CPG), and health care. Saama’s sales team had worked to
trim the funnel in the non-targeted vertical markets, but this left the company with the challenge of increas-
ing penetration within its chosen vertical market by securing more life sciences customers and by increasing
its share of wallet1 with existing customers. The company was also evaluating growth through new product
development to take advantage of recent advances in artificial intelligence (AI) and blockchain technologies.
Although Saama’s leaders had confidence in their vertical market strategy, they needed to decide the path-
ways for growth that would position the company for continued profitable growth.

Company Background

The Early Years (1997–2010)

Saama Technologies was founded in 1997 by Suresh Katta, a technologist with degrees in both electrical and
computer engineering. Katta wanted to leverage his lifelong love of mathematics to solve complex, data-in-
tensive problems. While working at computing manufacturer Silicon Graphics, Inc. (SGI), Katta met Sagar
Anisingaraju and Rajeev Dadia. At SGI, the trio worked with vast amounts of engineering data, building re-
porting capabilities for engineering stakeholders to gain insights from their data. Reporting systems at that
time typically were separate from business transactional (ERP) systems from companies like SAP. Reports
allowed companies to find answers to questions such as why transactions happened and why certain prod-
ucts were not selling well.

Katta realized that the work they were doing on analysis of engineering data could also be applied to the

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business side of the enterprise. This insight led him to found Saama. The company’s name was derived from
the Sanskrit word samaveda, meaning “book of knowledge.” Recalled Katta in an interview: “It was a risky
move. I promised my wife I would find a regular job if Saama wasn’t successful within one year. Luckily, things
worked out in my favor.”2

Saama’s vision was to allow clients to visualize and analyze what was happening in their business by con-
necting data from CRM systems, financial systems, and supply chain systems to get a “single version of the
truth” about their business. Saama helped clients convert the vast amounts of raw data stored across en-
terprises into actionable insights to drive business decisions. Katta’s intuition proved accurate, and Saama
secured three clients within 15 months. In the first year, the company chalked up $1.5 million in revenue,
and Katta brought on board his first employee, Larry Rosenblum, a Berkeley and Stanford graduate who had
worked at HP for 20 years. Katta handled sales and Rosenblum managed technical development and cus-
tomer support. Saama turned cash-flow positive within a year and revenues grew steadily to $3 million in Year
2, $6 million in Year 3, and $10 million in Year 4 of the business.

In 2000, Katta convinced another ex-SGI team member, Rajeev Dadia, to join Saama to run its client care
operations. He also wanted his other ex-SGI colleague, Sagar Anisingaraju, to join Saama, but Anisingaraju
had left SGI to start his own company in 1998.

Saama’s early growth came to a halt in 2001 with the dot-com bust. All of Saama’s clients were in Silicon Val-
ley, and the majority were technology companies, which were hard-hit by the dot-com bust and the recession
that followed it. Some of Saama’s clients even went out of business. Katta had to make the painful decision
to let several people go so Saama could stay in business. He managed to steady the ship, and the company
returned to profitability, but growth had plateaued.

By 2005, Katta realized he needed to diversify Saama’s business to avoid another crisis like the dot-com bust.
He embarked upon a diversification strategy and identified several new verticals, including the pharmaceu-
tical, CPG, and insurance industries. Genentech and Unilever became clients in 2007. Despite hitting some
bumps in the road during that year because of client defaults leading to a cash crunch, Saama continued to
grow. In 2010, Anisingaraju decided to merge his venture with Saama and came on board as the chief strat-
egy officer.

Moving From Services to Products (2011–2015)

By 2011, Saama was profitable and had grown to 500 employees, but Katta believed the company could
leverage two recent industry developments—innovation in algorithms and mathematics, and the increased
adoption of open source software—to pursue even bigger opportunities. The software and services industry
was also changing. As Katta noted: “Until this time, if you wanted to build a billion-dollar software company,
you could only do it through massive venture funding or you had to be SAP, Oracle, or Microsoft. By 2011,
this was no longer true. Entrepreneurs could build and grow a very big business without that kind of funding
or legacy.” In his role as chief strategy officer, Anisingaraju set out to design Saama’s own data and analytics
technology stack as its proprietary intellectual property (IP). Saama started with a modest IP footprint. “In the
beginning, it was the equivalent of making a button, while SAP was making a shirt,” Katta said. “Eventually
Saama could make not just the shirt but the most fashionable shirt, at that.” Anisingaraju and Katta were bet-
ting that competitors like SAP could not move as fast as Saama because they were too big and too beholden
to their legacy ERP business.

Katta and Anisingaraju formed a small steering team of engineers to build out solutions for finance, insurance,
and healthcare. Initially these solutions were customized, with few repeatable elements, but they brought in

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revenues and allowed Saama to fund IP development with client dollars. Over a four-year period from 2011
to 2015, clients like Cisco, PayPal, and Synopsis contributed millions of dollars towards the development of
Saama’s IP.

By 2015, Saama had assembled a powerful board of directors and an influential set of strategic advisors. The
board challenged Katta to pivot the business yet again. Revenues from IP-based products had reached a
third of total revenues, and the rest of the revenues came from services projects. Katta realized that a project-
based business was difficult to scale as it lacked the repeatable elements that would allow Saama to “produc-
tize” its services. The move to developing repeatable and scalable products would require significant capital
investments, which Saama, as a services company, had never done. The board advised Saama’s leadership
to raise new capital. A concerted fundraising effort led to commitments of $35 million from a single institutional
investor within a few weeks.

The injection of new capital allowed Saama to accelerate its evolution from a project-based services company
to an IP-based product company. Saama expanded its engineering team and structured its IP development
into a three-layered platform model. The bottom layer consisted of horizontal data infrastructure that could
be shared across vertical market applications. The middle layer consisted of industry-specific applications.
The top layer consisted of business outcomes for targeted applications. By segregating the horizontal layer
from the industry-specific layers, Saama could build products for a variety of industries on a common foun-
dation. Saama also hired professional product managers to manage its IP-based products. Karim Damji, who
had headed strategy and product management for other technology companies, came onboard to lead the
product management function. Damji also brought the discipline needed to deliver the four Ps of marketing:
productizing, pricing, packaging, and positioning.

Saama packaged its analytics offering as the Fluid Analytics Engine (FAE®), which employed advanced ana-
lytics models to produce actionable business insights (see Exhibit 1). FAE leveraged new technologies in big
data such as the Hadoop Distributed File System (HDFS) and MapReduce to store and process data. The
benefits delivered by FAE were speed of implementation, lower cost, and superior insights. FAE delivered
speedy solutions because it came with pre-built machine learning models containing advanced visualizations
and data management. By pre-building up to 70% of the functionality in the FAE backbone, Saama was able
to develop industry-specific solutions within three months. FAE also leveraged the client’s existing analytics
investments and could be delivered via the cloud, making it cost-effective. Importantly, by offering FAE to dif-
ferent industry verticals, Saama developed a deep understanding of the customer’s business and the vertical
market. Saama offered FAE-based solutions to the technology, media, insurance, life sciences, healthcare,
government, and CPG industries. Its clients included Cisco, Broadcom, GoPro, Astellas, Dignity Health, the
FBI, CSAA Insurance Group, Motorists Insurance Group, PayPal, and Unilever.

Narrowing the Market Focus (2016–2017)

Although FAE drove growth for Saama, Katta felt that the company had spread itself too thin by 2016. He
thought Saama was attacking too many verticals. “You always learn from the market, and you always learn
from the customer,” Katta explained. He came to the conclusion that Saama needed to reverse course by
narrowing its market instead of chasing clients in many different verticals. Katta met with Professor Mohan
Sawhney at the Kellogg School of Management to get feedback on his vertical market strategy. A comment
by Prof. Sawhney resonated with Katta: “No market is too narrow to build a billion-dollar company if you go
deep enough.” Katta became convinced that Saama had to focus on one vertical in which the company had
the most differentiated offering.

Based on an analysis of its clients, its domain expertise, and the attractiveness of the market, Saama chose

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the life sciences industry as its target vertical market. More specifically, Saama chose to focus on analytics
solutions for managing clinical operations in the life sciences industry. Clinical operations represented a big
opportunity because life sciences companies could take as long as 10 years to bring a blockbuster drug to
market and spend as much as $2 billion in the development process. Further, clinical operations were driven
by data and analytics, but this data was difficult to gather and analyze because it was stored in silos within
the company and it was collected from a wide range of third-party data sources. If Saama could create an
analytics solution that would unify the data sources and derive insights for clinical operations, it could shave
months and even years off the launch of new drugs.

Saama decided that it would keep its legacy customers in other verticals, but it would not invest in further
product development or actively pursue new clients in the off-target verticals.

The Life Sciences Industry and Clinical Operations
Life sciences is defined as all sciences that have to do with forms of life such as plants, animals, and human
beings. Life sciences companies focused on finding cures, eradicating diseases, and lengthening the life span
of human beings. The life sciences industry consisted of companies in the biotechnology, pharmaceuticals,
biomedical technologies, and biomedical devices sectors, along with companies involved in helping these
companies in R&D, as well as in the commercialization of their products.

The life sciences industry was a very research-intensive industry. Worldwide R&D spending by pharmaceuti-
cal and biotech companies was estimated to be $154 billion in 2016 and was projected to increase to $182
billion by 2020 (see Exhibit 2). In 2016, the average life sciences company spent 20% of its revenues on
R&D.

Clinical Operations and Clinical Data Management

Clinical trials are experiments or observations in clinical research on human participants that seek to answer
two key questions:

1. Does a prospective drug or device work? (Efficacy)
2. Is the drug or device safe? (Safety)

In the United States, clinical trials are conducted under the supervision and oversight of regulatory authorities
such as the Food and Drug Administration (FDA). These regulatory authorities are responsible for evaluating
the risk/benefit ratio of the therapy. Clinical trials typically proceed in three phases:

• Phase I involves testing the drug on 20 to 100 volunteers with the disease or condition. The goal is
to determine the optimal dosage to be given to patients and ensure patient safety. This phase costs
an average of $170 million and takes an average of 1.5 years.

• Phase II involves testing the drug on up to several hundred volunteers with the disease or condition
in order to measure the drug’s efficacy and possible side effects. This phase costs an average of
$400 million and takes an average of 2.5 years.

• Phase III involves testing the drug on 300 to 3,000 volunteers with the twofold purpose of further test-
ing the drug’s efficacy and monitoring for long-term adverse reactions or side effects (surfacing only
after one to four years of taking the drug). This phase costs over $500 million and takes an average
of 2.5 years.

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On average, then, clinical trials across the three phases cost over $1 billion and take 6.5 years. In 2015, al-
most 7,000 drugs and treatments were in development worldwide. The top three cost drivers of clinical trial
expenditures were clinical procedure costs (15–22%), administrative staff costs (11–29%), and site monitor-
ing costs (9–14%). Most important for Saama, 60% of clinical trial activities were data management related
and 20% of trial dollars were reserved for clinical data sciences. Life sciences companies struggled to keep
clinical trials on schedule and on budget. Fewer than 10% of trials were on budget and on time, whereas
about 40% were costly and over budget. Approximately 72% of trials were one month behind schedule, and
14% of trials were abandoned for a variety of reasons: safety concerns, insufficient or low enrollment, lack of
efficacy, withdrawal of funding support, withdrawal of the compound, or unavailable subjects. Patient recruit-
ment took 30% of the total time spent; 70% of studies experienced delays in patient enrollment, while 20%
failed to recruit a single subject.

Based on discussions with customers, Saama identified a pain point—life sciences companies found it difficult
to procure data from the diverse data sources they needed to access, and they found it difficult to get action-
able data. For instance, the site ClinicalTrials.gov provided useful macro data on clinical trials, but the data
was not granular enough to predict the enrollment rate of a given site or investigator.

Clinical data consisted of R&D (clinical operations data) and commercialization (real-world data). In a clinical
trial, the amount of data gradually increased as a drug moved from phase to phase. The biggest data prob-
lems arose in the more advanced phases, as a drug progressed toward market authorization and access and
into pragmatic trials and registries.

Saama’s discussions with customers revealed three key desired outcomes for clinical operations: operational
efficiencies, clinical trial effectiveness, and a streamlined submission process. These outcomes called for
clean longitudinal data, patient centricity, leveraging artificial intelligence, and bringing a Silicon Valley innova-
tion mindset to the arena of data solutions. The customer pain points suggested that the clinical development
process was ripe for disruption.

Sizing the Clinical Operations Analytics Market

To identify its TAM, Saama mapped all the places big data and analytics were used in the life sciences in-
dustry. Big data and analytics spend could be found in R&D, as well as in sales and marketing (commercial-
ization). A closer look at the R&D process indicated that roughly 20% of the R&D budget was spent on initial
research or pre-clinical activities and the remaining 80% on a combination of clinical trials (Phase I–Phase
III), regulatory approval, manufacturing, and post-market surveillance activities (see Exhibit 3).

The clinical trials component of the R&D process could be further divided into business processes that started
with the development of the protocol and continued with study startup, site activation, patient enrollment,
study conduct, and finally study closeout (see Exhibit 4). These business processes constituted the seg-
ments of Saama’s addressable market. The other area in which big data and analytics spend occurred was
for marketing and sales activities during the commercialization phase for the treatment or drug.

Combining the analytics spend in R&D with the analytics spend in marketing and sales, Saama estimated its
TAM to be $14.8 billion in 2017 (see Exhibit 5). A more meaningful measure was Saama’s total serviceable
market (TSM), the portion of the TAM that Saama could reach with its current channels and products. Saa-
ma’s TSM was limited to the clinical trials (Phase I–Phase III), post-approval safety trials (Phase IV), and the
sales and marketing component of commercialization. Saama estimated its TSM to be $7.23 billion in 2017.
Within this market, Saama limited its target market to two segments: pharma and biotechnology companies,
as well as contract research organizations (CROs) and contract manufacturing organizations (CMOs). This

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resulted in a target market size of $2.83 billion for Saama, 70% of which were pharma and biotechnology
companies and 30% of which were CROs and CMOs.

The total number of life sciences companies was between 500 and 600. About 20 large companies had more
than $10 billion in annual revenues, and 30 midsized companies had revenues between $1 billion and $10
billion. The rest were smaller companies of revenues between $100 million and $1 billion. In 2018, the large
companies accounted for almost 30% of the analytics spend in terms of the TAM and almost 50% of the ana-
lytics spend in Saama’s target market.

Building the Life Science Analytics Cloud (LSAC) Solution
In September 2017, Saama announced the launch of its Life Science Analytics Cloud (LSAC), which was de-
signed to optimize clinical development processes and deliver business outcomes by streamlining the steps
of the entire clinical data journey. Saama’s research had shown that process improvements and the use of
data standards could save the life sciences industry up to $6 billion annually. The LSAC offering used data
frameworks, smart data pipelines, therapeutic area-specific templates, and analytical assets to reduce time-
to-value and improve ROI for clinical development.

The LSAC offered a complete range of cloud-based clinical data analytics solutions and incorporated the lat-
est techniques in machine learning and deep learning to deliver results for the life sciences industry. With
LSAC, Saama was able to create a holistic view of the patient’s journey through a clinical trial, which was cru-
cial to identifying cohorts for clinical trial and tracking the treatments they received. The LSAC featured a cen-
tralized “clinical data lake” consisting of three information buckets: evidence generation around innovation,
data management and quality through automation, and insights and cost based on operational information.
Based on this data foundation, Saama created a suite of cognitive analytics products.

Saama’s LSAC solution included the following offerings (see Exhibit 6 and Exhibit 7):

• Clinical Development Optimizer (CDO), for monitoring and managing performance and risk of the
clinical trial portfolio

• Trial Planning Optimizer (TPO), for designing and optimizing clinical trials
• Cohort Builder, for identifying eligible patient populations for clinical trials
• Market Analyzer, for analyzing the market performance of pharmaceutical products
• Patient Pathways, for tracking the end-to-end patient journey through disease and treatment

The overarching benefit of the LSAC solution was to drive faster trials and better patient outcomes. This in
turn led to faster drug commercialization and reduction in total cost of ownership. LSAC allowed clients to de-
sign better trials, evaluate trial performance, derive valuable business insights, and proactively manage risks.
LSAC also leveraged existing infrastructure, which helped save money through shorter implementation and
deployment time frames.

Choosing a Growth Pathway
As Saama’s leaders gathered to chart the path ahead in October 2017, they were beginning to see their fo-
cused vertical market bet pay off. Saama’s life sciences business had shown explosive growth in excess of
50% year over year for three years in a row. Saama’s account and functional leaders were projecting simi-
lar 50% CAGR growth rates for the next three years. Key customers were starting to adopt Saama’s LSAC

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offerings. Industry accolades were arriving and Saama’s experts were presenting at pharmaceutical industry
conferences and being recognized as thought leaders. Saama’s AI research team distinguished itself through
groundbreaking work that was published in peer-reviewed technical journals. To build on the momentum, Saa-
ma’s leadership had identified three possible growth pathways.

Customer Acquisition Pathway

The first growth pathway was a “hunting” strategy that would involve acquiring new customer accounts for the
LSAC business. These could be entirely new accounts (“new logos”), or they could be Saama’s legacy life
sciences services customers who were new to the LSAC solution. Saama would target pharma and biotech
and CROs that represented a total target spend of $2.83 billion. This pathway seemed attractive, as Saama
had less than 5% market share and the market for analytics solutions was still in its infancy, with many cus-
tomers still to be acquired.

To estimate the revenue potential from new customer acquisition, Saama’s team divided the target market
into 20 large accounts (e.g., Pfizer), 30 midsized accounts (e.g., Actelion), and about 550 smaller accounts
(e.g., Ironwood Pharmaceuticals) based on annual revenues of the companies. For each segment, the team
estimated the annual analytics spend, the annual revenues Saama could expect from a typical account, the
length of the sales cycle, and the probability of closing a deal with prospective accounts. High-probability ac-
counts would close 50% of the time, while medium-probability and low-probability accounts would close 25%
and 10% of the time, respectively. Saama’s sales team estimated that it could close no large accounts, one
midsized account, and two small accounts in Year 1. In Year 2, it could close two large accounts, four mid-
sized accounts, and six small accounts (see Exhibit 8).

Acquiring new accounts was no easy task, however. Saama would have to compete with large system in-
tegrators, such as Accenture and Deloitte, as well as with the in-house development teams at life sciences
companies. Although system integrators tended to be deeply entrenched in most large accounts, they had of-
ten over-promised and under-delivered on analytics solutions. Saama would need to find beachheads in new
accounts by identifying specific pain points, such as patient enrollment or clinical trial portfolio management,
that mapped to a specific LSAC module like the Cohort Builder or Trial Portfolio Optimizer.

Success in new account acquisition would depend on the strength of Saama’s value proposition, the clarity of
the company’s story, and its ability to reach the right decision makers within the organization. Saama would
need to lean heavily on two or three of the senior executive team members to close strategic deals. To short-
en the sales cycle, Saama could employ a pilot program in which it could offer one specific LSAC module for
a 30-to 60-day trial at a relatively low price to help customers gain confidence with Saama’s solutions and
capabilities.

Customer Development Pathway

In contrast to the customer acquisition (“hunting”) strategy, the customer development (“farming”) strategy re-
lied on increasing the share of wallet among current LSAC customers by broadening Saama’s footprint within
an account with adjacent products, as well as by deepening its penetration within the account by selling to
other business units or clinical groups within the account. Saama estimated that the typical analytics spend
for a large life sciences client was around $100 million per year. Saama’s current deployments brought in
around $2 million, representing a mere 2% share of wallet for a large account. This suggested that large and
midsized accounts had significant potential for increasing share of wallet. Small accounts would be excluded
from the customer development pathway, as the opportunities to broaden and deepen Saama’s footprint were
limited in that type of account.

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In broadening the scope of its offerings within a client account, Saama would have to position itself as a “best
of suite” provider with a superior end-to-end analytics solution, as opposed to point solutions or more narrowly
focused solution providers. Saama would need to compete against a wide variety of focused competitors who
might have capable point solutions that did not necessarily work well with Saama’s offering. Saama would
need to convince clients to “rip and replace” these point solutions or it would need to co-exist and integrate its
solution with the point solution providers chosen by the clients.

Saama’s typical LSAC client signed up for only one LSAC module. Saama could broaden its footprint within
an account by cross-selling additional LSAC modules to the client. For instance, Saama could focus on a
CDO client and sell it related modules, such as TPO. Saama estimated that the average large account could
buy three additional modules at an average of $500,000 per module per year and that midsized accounts had
the potential to buy two additional modules at $250,000 each per year. The company estimated that in Year
1, it would close no large accounts and only one midsized account for cross-selling deals. It estimated that in
Year 2, it would close one large account and four midsized accounts.

Saama could also deepen its penetration within an account by selling into other therapeutic teams within a
client account. For instance, if Saama were working with the oncology therapeutic team at a large pharma
client, other therapeutic areas at the client could also benefit from Saama’s solutions. To be successful at
cross-selling to other clinical trial teams, Saama would need to secure glowing references from existing
stakeholders. Saama would need account managers to work with operational directors and managers in the
client’s organization, showing them improved business value from Saama’s solutions and thereby spearhead-
ing growth through proven results. On average, an account expansion deal would lead to an additional $1
million from a large account (two additional therapeutic areas at $500,000 each) and $250,000 from a mid-
sized account (one additional therapeutic area at $250,000 each). The company estimated that in Year 1, it
would close one large account and two midsized accounts for account expansion deals. It estimated that in
Year 2, it would close three large accounts and four midsized accounts.

Saama could also address adjacencies such as compliance, patient sentiment, and managed care solutions.
These adjacencies represented expanded feature capabilities within the established focus area and would
require Saama to manage a broader set of subject matter expertise and client delivery capabilities, along with
salespeople who were multifunctional and skilled at cross-selling multiple products and the whole LSAC plat-
form.

Product Development Pathway

The third growth pathway for Saama was investing in transforming its products and solutions to take advan-
tage of recent developments in technology. In recent years, the technology industry had witnessed dramat-
ic advances in two areas: artificial intelligence and blockchain technologies. These were nascent areas, so
the analytics spend on these technologies was not yet well known. However, Saama’s leadership team was
convinced that these two technologies had the potential to disrupt the analytics marketplace by creating new
paradigms for developing analytics models, as well as for managing clinical trial workflows. Saama’s current
analytics solutions could be enhanced with these technologies but could also be commoditized by the same
technologies. The likely outcomes were not yet clear.

Artificial Intelligence and Deep Learning

Artificial intelligence was a field that had existed for several decades in academic institutions and large tech-
nology companies. In recent years, however, AI had hit an inflection point due to the creation of open source

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tools from companies such as Google, Microsoft, IBM, and Amazon, as well as advances in computational
engines (GPUs) and cloud computing. Open source tools and wide availability of powerful computing engines
had leveled the playing field in the analytics industry. Smaller and nimbler startups now had access to some
of the same algorithmic work that propelled technology giants such as Facebook, Google, Amazon, and Mi-
crosoft. Every major technology company, including system integrators, system of record providers, and ana-
lytics solution providers, was investing heavily in AI and deep learning3 technologies. Saama realized that it
needed to embrace AI and deep learning as a competitive necessity. It created an internal AI research team
with a charter to develop, test, and iterate new AI-enabled analytics solutions.

Saama’s AI research team identified several areas where AI could enhance clinical analytics, including patient
selection for clinical trials, predictive feasibility models, natural language–based prediction of adverse events,
intelligent virtual assistants, and clinical trial cost predictions.

Exhibit 9 shows an example of how Saama had augmented its LSAC platform with just one AI application:
natural language understanding (NLU). Saama’s AI team realized that close collaboration with leading-edge
clients would be crucial to identify promising use cases for AI. To drive co-development with customers, the
team created a program called Innovation.AI. In this program, Saama would work with a selected set of clients
to design experiments for AI applications in clinical operations. Saama would bring technology expertise, and
the client would contribute data and the business problem to be solved with AI.

Saama created an initial list of candidate use cases for AI in clinical operations. These included intelligent
virtual assistants for clinical trials, predicting insurance claims for fast-track submissions, and adverse events
to drug mapping using NLU. The Innovation.AI projects were one-time pilots and were valued at $100,000
for midsized customers and $250,000 for large customers. Saama estimated that 50% of pilot engagements
would convert into scaled-up AI projects, with a value of $500,000 annually for midsized accounts and $1
million annually for large accounts. In Year 1, Saama expected to secure one pilot project with large cus-
tomers and two projects with midsized customers. In Year 2, it expected to double the number of pilot projects
and would begin to realize revenues from scaled-up engagements that began as pilots in Year 1. In Year 1,
revenues from the AI engagements would be limited to revenues from one-time pilot projects. In Year 2, rev-
enues would include one-time pilot projects as well as recurring revenues from scaled-up engagements.

Besides the revenue outcomes from Innovation.AI experiments and AI engagements, Saama would also ben-
efit from being perceived as a trusted advisor and thought leader for its life sciences customers. In addition,
embedding AI models into its LSAC modules would increase competitiveness of the core LSAC offering and
serve as a defense mechanism to prevent commoditization of the LSAC platform. However, the revenue po-
tential from AI-related products and solutions was quite uncertain.

Blockchain

The blockchain is an incorruptible digital ledger of economic transactions that can be programmed to record
not just financial transactions but virtually everything of value.4 By creating a distributed ledger of transac-
tions, blockchain creates an indelible record that cannot be changed; furthermore, the record’s authenticity
can be verified by the entire community using the blockchain instead of a single, centralized authority. Al-
though blockchain technology initially was applied to financial transactions in cryptocurrencies like Bitcoin, the
technology could be used to record, verify, and manage any transaction or contract among multiple parties.

Blockchain had the potential to be a significant disruptor to the entire life sciences ecosystem. From a vendor/

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competitive perspective, it democratized data and made it more accurate. This meant that the competitive
advantage currently enjoyed by Saama in ingesting and harmonizing of data could be eliminated. Access to
troves of data also did not present a barrier to entry for analytics vendors accessing the blockchain. Phar-
ma companies and CROs could get rid of many processes for cleaning and verifying data as the blockchain
made these issues moot. Blockchain represented a serious threat for system-of-record vendors as their sys-
tem workflows would get severely altered or even eliminated. Pharma companies and CROs would also have
access to benchmarking data across companies if everyone agreed to put their data in a blockchain ledger.
Patients could also have more control over their data and could even be in a position to monetize their data.

Saama needed to identify the most promising use cases for blockchain in clinical operations, and it needed to
figure out how to create a viable business model for blockchain-based offerings for these use cases. Saama’s
R&D team zeroed in on three big challenges in contemporary clinical research: patient enrollment in clinical
trials, personal data privacy concerns, and data sharing. Clinical studies were often compromised by errors or
fraud, resulting in a lack of inviolability or reproducibility. Blockchain could address this problem by providing
a transparent, decentralized technology wherein the data was secured and hardcoded by a complex, crypto-
graphic algorithm. In addition, the decentralized ledger would give users a great deal of control and autonomy
over the data and could lead to improved trust in the efficacy of the clinical trial process.

To illustrate the power of blockchain in clinical trials, consider a specific use case of informed patient consent.
One of the key problem areas in the conduct of a successful clinical trial was to capture and manage patient
consent for all applicable protocol amendments. As clinical operations are digitized, patient consent forms
could be captured digitally. However, issues such as proper time stamping, omissions, and fraud had creat-
ed major bottlenecks for the timely verification for approvals. Blockchain’s Smart Contracts would solve this
problem. See Exhibit 10 for more details on clinical trial data workflows enabled by blockchain technologies.

Although Saama had started experimentation with blockchain, much uncertainty remained regarding the
blockchain ecosystem, as well as business models for monetizing blockchain offerings. Saama’s R&D leaders
were actively engaging with industry forums and participating in pilot programs to vet blockchain technologies.
Through these activities, Saama’s team hoped it would gain insights into use cases and business models for
blockchain in clinical operations.

Conclusion
Saama’s leadership team had distilled its growth opportunities and challenges into three key questions:

1. What growth pathways would best enable Saama to fulfill its vision of becoming the mar-
ket leader in the life sciences clinical analytics space?

2. Which growth pathways best fit with Saama’s capabilities?
3. What are the risks and implementation challenges for each growth pathway and how can

they be mitigated?

By identifying the best growth pathways and being cognizant of the risks and challenges of its chosen path-
ways, Katta and his team hoped that Saama would be able to maintain its fast-growth trajectory.

Notes

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1. Share of wallet is the percentage of a customer’s total spending that a business captures with its products
and services.

2. All quotations from Suresh Katta are from an interview with the author, October 30, 2017.

3. Deep learning is a subset of a broader family of machine learning methods based on learning data repre-
sentations as opposed to task-specific algorithms. Deep learning models feature multiple layers of nonlinear
processing units that correspond to different levels of abstraction; the levels form a hierarchy of concepts that
progress from specific to more abstract concepts. Deep learning models are inspired by information process-
ing and communication patterns in a biological nervous system, such as neural networks in the human brain.

4. Don Tapscott and Alex Tapscott, Blockchain Revolution: How the Technology Behind Bitcoin Is Changing
Money, Business, and the World (New York: Portfolio/Penguin, 2016).

http://dx.doi.org/10.4135/9781526491930
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Saama Technologies: Growth Through a Focused Vertical Market Strategy

http://dx.doi.org/10.4135/9781526491930

Saama Technologies: Growth Through a Focused Vertical Market Strategy
Case
Abstract