case study

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Nursing Care of the Patient
With Endocrine Disease

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Køren K. Gi,ttùngs

Unfolding Case Study #36 T,, Jenny

Jenrry is a56-year-old female who is scheduled for a routine primary care provider’s
(PCP) visit to follow-up on her hypertension. She reports no signi-ficant complaints
other than her vision being blurry; she states, “I need to go to the eye doctor t

o

have my eyes checked.” At the conclusion of her visit, the PCP orders a basic meta-
bolic panel (BMP) and complete blood count (CBC) to be drawn. Jenny receives a
phone call 2 days later from her PCP’s office to schedule an appointment for later
that day. Jenny is told that her blood sugar is elevated. At her appointment, Jenny
and the nurse begin by reviewing Jenny’s risk factors for diabetes.

Exercise 6-lz Select øl.l tltøt øþþly
Identify risk factors commonly associated with diabetes mellitus:

E Obesiry
fl ege less than 45 years
E Caucasianrace
I Family history
D History of gestational diabetes
E History of delivering babies over 9 pounds

eResource 6-l: To review risk factors associated with diabetes, consult
Epocrates Online: [Pathway: -+ hnpt//online.epocrates.com -> select the
“diseases” tab -+ enter “Diabetes” into the search field -+ review content
related to “risks”]

Jsnny reports that her mother and grandmother were diabetics. She is also over
45 years old and overweight at 5 feet 2 inches anld 2OO pounds. Jenny still finds it
hard to believe that she could be diabetic since she is feeling okay; she asks the
nurse to explain to her how diabetes occurs.

Anstpers to tbis cbapter begin on page 23

1

215

216 CHAPTTR 6: ENDOCRINE DISEASE

Exercise 6-22 Multiple-cltoí.ce question
The nurse educating Jenny on type 2 diabetes determines that she understands tþs
information when she states:

A. “I am not producing any insulin because of a problem with my immune
system.”

B. “I will need to take insulin for the rest of my life.,’
c. “I’m not making enough insulin or my body isn’t as sensitive to it.,,
D. “I won’t need to make any dietary changes if I take my medicine.”

Exercise 6-32 Møtcbing
Match the type of diabetes in Column A with its typical characteristics in Column B
Answers in Column A can be used more than once.

ColumnA Column B
A. Type L diabetes Onset is usually under 30 years old
B. Type 2 dial¡etes patient is often thin at time of diagnosis

Treated with diet, exercise, and oral agents

Patient is often obese at time of diagnosis

Antibodies are present in the body

Patients require insulin for life

G) ;ffi::i,””,’J ^ä¿'”äîîî#.”å:*t’#i;:lË:iffi,îå:ä. _enter “Type 2 Diabetes” into the search field -+ in the “overview,’section,
select “pathophysiology” and

review content]

By the time it is Jenny’s turn to see her PCP, she has a beginning understanding
about diabetes. Her PCP sits with her and begins by reviewing hãr hboratory re-
sults. Her fasting plasma glucose from her last visit was 236 mg/dL.The pCp lists
some typical signs and symptoms of diabetes, and he asks Jenny if she is experi-
encing any of them.

Exercise 6-4: Select ølt tbat øþpty
Identify coÍunon clinical manifestations associated with diabetes mellitus

E rolyuria
E Decreased appetite
Q Decreased fluid intake
E Vision changes
fl natigue
eResource 6-3: For more information regarrding clinical manifestations
associated with diabetes mellitus, refer to the Merck Manual: fpathwayt
www.merckmanuals.com + select “Merck Manual of Diagnosis and

o
Answers to tbis cbapter begin on page 2J1

CFIAPTER 6: ENDOCRINE DISEASE Questions 217

o

Therapy” –> enter “Diabetes” into the search field + select “Diabetes
Mellitus (DM)” -à select “Symptoms and Signs” and review content]

Jenny reports that her vision has been blurry, but she thought that she needed
new glasses. She also recognizes that she has been drinking and urinating more
than usual. Based on her symptoms and elevated fasting plasma glucose, the phy-
sician suspects Jenny has type 2 diabetes.

eResource 6-4: To learn more about the diagnostic work-up for Jenny,
refer to Medscape on your mobile device: [Pathway: Medscape *) enter
“Type 2 Diat¡etes” into the search fleld + select “Type 2 Diabetes
Mellitus” -+ select “‘$7’orkup” and review content]

To further confirm the diagnosis, he orders a random fingerstick blood sugar and
Hemoglobin A1C (HgbAlC).

Exercise 6-52 Sbort ønsu)er
Briefly explain how a HgbAlC is used to evaluate blood glucose compared to a ran-
dom blood glucose level.

o eResource 6-5zTo learn more about HgbAlC, refer to Medscape on yourmobile device: [Pathway: Medscape -+ enter “A].C” into the search field -+
select “Hemoglobin A1C testing”and review content]

Jenny’s blood results are ready within a short period of time. Her fingerstick blood
sugar is 286 and her HgbAlC is 9%. Her physician orders metformin 500 mg
orally twice a day, andJenny is scheduled to meet with a diabetes educator in2 days.

Exercise 6-6: Fill-in
Identify three ways in which metformin acts to maintain normal blood glucose levels:

1

2

3

o eResource 6-6:To review patient teaching regarding metformin withJenny, refer to Epocrates on your mobile device: [Pathway: Epocrates ->
enter “metformin” into the search field + select “metformin” -) scroll
down to review “common reactions” and other relevant content]

Jenny meets with the diabetes educator as scheduled. During her appointment,
they discuss many topics including nutrition and exercise. The educator begins by
talking about meal planning and caloric needs.

Anstaers to tbis cba.pter begin on page 231

218 CHAPTER 6: ENDOCRINE DISEASE guestions

rxefcrse o- / 2 .Íttt-Nt .
For obese patients who are diabetic, the key to treatment is:

Exercise 6-8: Fùll-in
Identify the food groups that are part of the Exchange List system and give one ex-
ample of a specific food within each group:

Exercise 6-9: True orfølse
Identify whether the following statements about nutrition in the diabetic patient are
true or false:

1. Soluble fiber lowers blood glucose levels by slowing the rate of
glucose absorption from these foods.

2. Alcohol used in combination with chlorpropamide

(Diabinese

)

may cause facial flushing, warmth,.rrauseal and vomiting.

3. Nutritive sweeteners have no effect on blood glucose levels.

Exercise 6-l0t Multìple-cltoíce question
The nurse educating Jenny on exercise determines that she needs further instruction
when she states:

A. “Exercise will lower my blood glucose level.,,
B. “I should try to exercise at the same time each day.,,
C. “Walking is generally a safe form of exercise.,’
D. “I should exercise more when my glucose levels are more than

25O mgldL;’

o eResource 6-72 To learn more about nutritional management of patientswith diabetes, refer to Medscape on your mobile device: [pathway:
Medscape -+ enter “nutrition” into the search field -+ select “Nutritional
Management of Patients with Diabetes” and review content]

Jenny is given a blood glucose monitor with instructions for self-monitoring of her
glucose levels. Once Jenny’s blood glucose level is stabilized, she is instructed to
test at least fwo to three times per week.

1.

2.

3.

4.

5.

6.

7.

8.

Ansuters to tbis cbapter begin on pøge 2J1

CHAPTER 6: ENDOCRINE DISEASE Questions 219

Exercise 6-ll: Select øll tltøt øpply
Identify other ci¡cumstances in which more frequent testing is recommended:

D Missing a mealtime
Ü Symptoms of hypoglycemia
I Changes in medications
E During periods of increased stress
E Times of illness

The diabetes educator explains to Jenny how metformin works to control her
blood glucose level. Jenny expresses concern that she may have to use insulin if
the metformin is ineffective, but the nurse explains that there are many other oral
agents availat:le that can be tried before moving to insulin.

Exercise 6-l2t Mø.tcbing
Match the medication in Column A with its drug classification and action in Column B.

ColumnA
A. chlorpropamide

(Diabinese)

B. glipizide
(Glucotrol)

C. metformin
(Glucophage)

D. acarbose
(Precose)

E. nateglinide
(Starlix)

Column B
Alpha-glucosidase inhibitor; delays intestinal
absorption of complex carbs
First-generation sulfonylurea; stimulates beta
cells of the pancreas to secrete insulin

Nonsulfonylurea insulin secretagogue;
stimulates th.e pancreas to secrete insulin
Second-generation sulfonylurea; stimulates beta
cells of the pancreas to secrete insulin
Biguanide; inhibits production of glucose by
the liver

o eResource 6-8: To learn more about these medications, consultMedscape on your mobile device: [Pathway: Medscape -) enter “Type Z
Diabetes” -+ select “Medication” and review content]

As Jenny’s appointment draws to an end, the diabetes educator teaches her about
hypoglycemia and long-term complications.

Exercise 6-15: Multiple-cltoice question
The nurse educating Jenny on hypoglycemia determines that she understands the in-
formation when she states:

A. “I won’t get hypoglycemic when I am only taking metformin.,’
B. “If I feel my blood sugar dropping, I will eat some chocolate candy)’
C. “My family should be educated on how to help me if I become hypogþemic.”
D. “Hypoglycemia most often occurs t hour after meals.”

Anstaers to this cbapter begin on þage 231

220 CÉ{APTER 6: ENDOCRINE DISEASE Qøes¿loøs

Exercise’ 6-14: Fnll-nn
Identify the macrovascular and microvascular complications that can occur witlì
diabetes:

Macrovascular Microvascular
L

eResoufce 6-9zTo learn more about microvascular and macrovascular
complications, refer to Medscape on your mobile device: [Pathway:
Medscape -+ enter “Type 2 Diabetes” -> select “Treatment and
Management” -) select’Approach and Considerations” and scroll down
to review contentl

Exercise 6-15: Select øll tÍtøt øpply
Identifiz foot care techniques recommended for diabetic patients

B Assess feet daily
E Lotion the feet, especially between the toes
fl Use hot water for soaking the feet
D trim toenails straight across
E Never walk barefoot

o eResource 6-LO: To supplement patient teaching regarding diabetes,refer to:
I MedlinePlus’s interactive tutorial, Dia.betes-Introduction:

http://goo.gl/nJn7B
I National Institutes of Health’s (NIH’s) pamphlet, Your Guid.e to

Diabetes: Type 1 and Type 2:http://goo.g/bgBNl

eResource 6-L1: To learn about the American College of Physicians
recommended vaccinations forJenny to help keep her healthy, download
the ACP Immunization Advisor (ACP-IA) “app” onto your mobile device
(http://goo.gllNzQlB). [Pathway on your mobile device: ACP-IA ->
select “frrud” -+ enter “age” aîd “Condition” (Note: There are no special
considerations for Jenny) -+ select “Show Vaccines”]

Unfolding Case Study #37’% Lorrie

Lorrie is a 60-year-old female who was recently diagnosed with hypothyroidism.
Her granddaughter, Alissa, who is in college studying to be a registered nurse, is
very interested in learning more about hypothyroidism so that she can help to
educate her grandmother about her disease process. Alissa begins by reviewing
basic anatomy and physiology of the thyroid gland.

1
2
3
2
o
o

Ansuters to this cbapter begin on page 2Jl

CI-L{PTER 6: ENDOCRINE DISEASE Qøestlo’?s 221

Exercise 6-16z Select øll tltøt aþþly

ldentrfy the hormones released by the thyroid gland:

B ftryroxitte (T4)
Q Thyroid-stimulating hormone (TSH)

E Triiodothyronine (T3)
E calcitonin
E ,tntidiuretic hormone (ADH)

Exercise 6-17: Fíl’l-i.n

Essential for the synthesis of thyroid hormones,

through diet.

Exercise 6-7.82 Sbort a’nsu)er

Briefly explain how the release of thyroid hormone is regulated in the body.

is obtained

o eResource 6-L2:To learn more, Alissa refers to Medscape on hermobile device: [Pathway: Medscape -+ entef “hypothyroidism” -+ select
“Ovefview” -) review content listed under “Background,” “Epidemiology,”
and ” PathophysiologY”J

Alissa is aware that many endocrine disorders have general signs and symptoms,

which may be initially ignored or thought of as being a part of the normal aging
process. Áirr” asks her grandmother what types of signs and symptoms she was
experiencing.

Exercise 6-t9z P¡l’Lín
Identify three common signs and symptoms that may indicate an endocrine disorder:

1.
)
3.

eResource 6-t3:To learn more about coÍunon signs and symptoms
associated with an endocrine disordeq refer to the Merck Manual:
I Hypothyroidism: [Pathway: www.mefckmanuals.com -) select “Merck

Manual of Diagnosis andTherapy” -+ entef “hypothyroidism” into the

search field + select “hypothyroidism” -+ select “symptoms and Signs”
and review content]

I Endocrine Disorders: [Pathway: www.merckmanuals’com -t select
“Merck Manual of Diagnosis and Therapy” -) enter “Endocrine
Disorders” into the search field -+ select “Endocrine Disorders” and

review content]

Answers to tbis cÍra’Pter begin on page 231′

222 CIIAPTER 6: ENDOCRINE DISEASE

Lorrie tells her granddaughter that she had been feeling very tired and hadenergy for cleaning the house or family activities. Because she didn’t initiallyanything was really wrong, Lorrie did not seek medical attention, but waitedher regularþ scheduled púmary carcprovider’s (PCp) appointment 3 monthsto mention her fatigue. Her pCp ordered some laboratory tests to be done onday and scheduled her for a follow_up appointment in 1 week.

Exercise 6-2O: Select ølt tbøt øppty
Identify clinical manifestations associated with hypothyroidism:

fl weight loss
E Fatigue
E lrritability
D Hair loss
D Increased pulse
fl Feeling cold in awarmenvironment

oË,i::ä::’i”‘,ÍJ;,’;î:å,ä?T3:ï:”i:,;å:1f, ,ffi,î1ïï:’,1îî::”n
field -+ select “crinicar presentation” and r*i.* åontentl

Exercise 6-2Iz LIøtcttí.ng
Match the laboratory test in column A with its description and normal value in
Column B.

ColumnA
A. TSH

B. T3

C. T4

D. Free T4

Column B
_7Û%o is protein-bound; normal is 5 to L.). mcg/dL

Direct measurement of unbound thyroxine;
normal is 0.8 ro 2.7 ng/dL

Best screening test for thyroid function; normal is
0.4 to 4.2 nIU/L

_ More accurate indicator of hyperthyroidism;
normal is 70 to 204 ng/dL

o;::,:ö::,9″ïJ;,Y:ååË3:ï:i:ffi :,”;,;ffi,T*,,in,o,he
search field -+ select “work-up” -> select

,,íiboritory studies,,and review
contentJ

At her follow-up appointment, Lorrie received her diagnosis of hypothyroidismand was started on levothyroxine (synthroid) 0.075 *g”or”tiy daily.Later,Alissa
reviews the medication with her grandmother so that sãe clearly understands theneed to continue taking it as direited.

Anszaers to tbß cbapter begin onpage 2J1

CHAPTER 6: ENDOCRINE DISEASE Questions 223

Exercise 6-22: True orla.lse
Identify whether the following statements about thyroid hormone replacement ther-
apy are true or false:

1. TSH levels are used for monitoring the effectiveness of thyroid
hormone replacement and in making dosage adjustments of the
medications.

2. Signs of overdose are manifested as hyperthyroidism (tachycar-
dia, weight loss, nervousness, and/or chest pain).

3. Thyroid hormone replacement is only needed until symptoms
subside; the medication can then be discontinued.

eResource 6-16z To learn more about this medication, Alissa consults
Epocrates on her mobile dêvice: [Pathway: Epocrates -+ enter “synthroid”
into the search field + review contentl

@

Since Lorrie has only recently been diagnosed with hypothyroidism and started on
levothyroxine (Synthroid), she continues to have some- clinical manifestations that
she did not previously know were related to the hypothyroidism. Lorrie continues
to tire easily, feel cold despite’warmer environmental temperatures, and struggle
with constipation. Alissa has found some nursing interventions through her study
of hypothyroidism tl:rat may be useful to her grandmother.

Exercise 6-23: Multiple-cltoi.ce questíon
V/hen educating her grandmother on controlling her fatigue, Alissa determines that
she understands the information when she states:

A, “I should push to get all of my housework done in one block of time.”
B. “f don’t want to ask for help; I need to keep pushing myself.”
C. “I need to get used to feeling tired since I will feel like this the rest of my life.”
D. “I need to space my activities so I can rest in befween.”

Exercise 6-242 Multþle-cboice qaesti.on
\Øhen educating Lorrie on how to maintain a normal body temperatt)re, her grand-
daughter determines that she needs further instruction when she states:

A. “I can just layer my clothing to provide more warmth.”
B. “I can use heating pads or an electric blanket when I go to bed.”
C. “I should stay aw^y from cold, ûafty areas.”
D. “I won’t feel cold all the time once my medicine starts working.”

Exercise 6-25: Select øll tbøt øþþly
Identify interventions designed to improve constipation:

D use laxatives regulady
D Increase fluid intake if no restrictions
E Increase activity as tolerated
E Use enemas on a biweekly schedule
fl Increase fiber content in diet

Anstuers to tbis cba.pter begin on þage 231

224 C}IAPTEP. 6: ENDOCRINE DISEASE

o Ilypothyroid.ism: lvba.t Euery parient Needs toeResource 6-172 Fot more patient education informafion, referKnout:
Alissa has compreted her study of hypothyroidism and educated heron her disease process, but she decides to review a rittle information
roidism since she knows that this can occur as a result of ingestion
thyroid hormone.

Exercise 6-26: Select øil tba.t øþþty
Identift clinical manifestations associated with hyperthyroidism:

on
of

fl Nervousness
fl Heat intolerance
E Progressive weight gain
Ü Poor appetite and decreased intake
D Tachycardia

Exercise 6-27. F¿lt-irt
Identify three atypical signs and symproms of hyperthyroidism rhat the elderþ
may present:

Gl eResource 6-rg: Arissa uses Medscape on her mobile device tov supplement her_understanding of hyperthyroidism: [pathway: Medscape-) enter “hyperthyroidism” into the sãarch field -+ rãview contentl

Exercise 6-28: True orføtse
Identifir whether the following statements about laboratory results used to diagnose
hyperthyroidism are true or false:

1. TSH levels are decreased with untreated hyperthyroidism.
2. Free T4 levels are decreased with untreated hyperthyroidism.

1.
)

:).

Unfolding Case Study #jg % finda
Linda is a 59-year-old femare with a medical history of hypertension, asthm a, andchronic bronchitis. sle ha_s a pasthistory of smoking orré ,o one and aharfpacksof cigarettes per day for 35 years. Linda quit smokin! when her asthma worsened;she has been smoke-free for 3 years now. As part of her treatment regimen, Lindahas been takingprednisone 2o mg oru:|ry dairy forthe past ii ,rrorrtrrr. at her mostrecent primary care provider’s (PCP) appointment, ;”iida expresses concern at the

Ansuters to tbis cbaþter begin on þage 231..

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