Please read the instructions carefully

Name: ________________________________

INTERP. CARE II

System Assignment

Endocrine System

The purpose of this assignment is to ensure that you are working diligently to keep up with the material and to give you practice both researching answers and answering questions specifically and succinctly.

To receive credit for this assignment, your answers must be in your own words, and:

❏ well-written, with terms correctly spelled.

❏ NOT copied from any course handouts.

❏ NOT be copied from your or any other textbook (with the exception of definitions);

❏ NOT be identical to another student’s answers.

The due date for this assignment will be announced in class.

Due date: ____03/12/2021____________ # Points: 50

S10

1.

Definitions. Provide a simple, concise definition for the following terms:

hormone

colloid

humoral

adenylate cyclase (a.k.a. adenylyl cyclase)

tropic hormone (tropin)

downregulation

glucocorticoid

2. Match the labels on the figure with the terms below.

J

I

H

F

E

D

C

B

A

____ adrenal gland

____ hypothalamus

____ ovary

____ pancreas

____ parathyroid gland

____ pineal gland

____ pituitary gland

____ testis

____ thymus

____ thyroid gland

G

3. Match the hormones listed below with the correct gland from Question 2.

estrogens and progesterone

gonadotropins (FSH and LH)

glucocorticoids

insulin and glucagon

many releasing hormones (e.g., GnRH,GHRH.) melatonin

mineralocorticoids

para

thyroid hormone

prolactin

T-cell stimulating hormones (e.g., thymopoietin,thymosin)

testosterone

thyroid hormone

4. List four examples of how cells can respond to hormones:

1.

2.

3.

4.

5. Explain why all cells do not respond to all hormones.

6. Match the hormones below with the type of stimulation to which they respond.

testosterone

insulin A. neural stimulation calcitonin

antidiuretic hormone

estrogens B. hormonal stimulation

TSH GnRH

parathyroid hormone C. humoral stimulation

norepinephrine

7. Do peptide hormones have cell-surface or intracellular receptors? Why?

8. Briefly explain the differences in activity between the following types of G proteins:

Gs

Gi

Gq

9. Do steroid hormones have cell-surface or intracellular receptors? Why?

10. How does a steroid hormone typically affect a target cell’s activity? What cellular components are involved in the target cell’s response?

11. Briefly describe the organization of the tissue in the pituitary gland.

12. Why is the anterior pituitary often referred to as the “master” endocrine gland?

13. Imagine you work for a pharmaceutical company and you have designed and synthesized a hormone-like molecule that (you hope) can be used in the treatment of diabetes. When you test this molecule in mice, you find that it has a half-life (t½) of 24 seconds. What does this mean?

14. Complete this concept map on the regulation of blood glucose levels by hormones of the pancreas.

15. Explain whether these two hormones are synergistic or antagonistic.

2

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