What does 50,045 in the Alkalinity calculation formula, alkalinity = (Vol. of Acid x Normality of Acid x 50,045)/(vol. of sample ) mean and how is it derived?

What does 50,045 in the Alkalinity calculation formula, alkalinity = (Vol. of Acid x Normality of Acid x 50,045)/(vol. of sample ) mean and how is it derived?

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